Others who managed to escape the blaze included Sir Richard’s 90-year-old mother, Eve, and his daughter Holly, 29.
Sir Richard, who bought Necker, in the British Virgin Islands, for around £200,000 in 1981 and began building the Great House the following year, was staying at a neighbouring property with his wife, Joan, and son, Sam, 25.
Guests including Academy Award-winning actress Kate Winslet escaped uninjured when fire destroyed Richard Branson's Caribbean home in the middle of the night, the British businessman said Monday.
The Virgin Group boss said about 20 people, including Winslet and her children, were staying in the eight-bedroom Great House on Necker, his private isle in the British Virgin Islands.
Branson said he was staying in another property around 100 yards away with his wife, Joan and son Sam, 25.
Winslet's spokeswoman, Sara Keene, confirmed the actress was unharmed.
Branson said the house was "completely destroyed" and the fire was not entirely out Monday.
Branson, 60, bought the island in the early 1980s and began building the Great House in 1982.